GREGoRi Innovation Projects (U01 Clinical Trial Optional)
$7,500,000
HHS-NIH11
POSTED: 06/18/2026
UPDATED: 06/18/2026
DUE: 10/30/2026
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular tech...
GREGoRi Technology Integration Center (U01, Clinical Trials Optional)
$3,000,000
HHS-NIH11
POSTED: 06/18/2026
UPDATED: 06/18/2026
DUE: 10/30/2026
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular tech...
GREGoRi Data Coordination and Outreach Center (U01, Clinical Trials Not Allowed)
$2,000,000
HHS-NIH11
POSTED: 06/18/2026
UPDATED: 06/18/2026
DUE: 10/30/2026
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular tech...
Environmental influences on Child Health Outcomes (ECHO) Cohort Data and Biospecimen Access (X01 Clinical Trial Not Allowed)
HHS-NIH11
POSTED: 06/18/2025
UPDATED: 06/18/2025
DUE: 03/01/2028
The purpose of this Program Announcement with Special Receipt, Referral, and/or Review Considerations (PAR) is to solicit applications to access limited identifiable data or biospecimens from the ECHO...
Blueprint MedTech Translator (UG3/UH3 - Clinical Trial Optional)
HHS-NIH11
POSTED: 06/17/2025
UPDATED: 06/17/2025
DUE: 01/28/2028
The purpose of this announcement is to encourage investigators to pursue translational activities and clinical feasibility studies to advance the development of therapeutic, and diagnostic devices fo...
Expanding the Target Landscape by Drugging the Undruggable (R21 Clinical Trial Not Allowed)
HHS-NIH11
POSTED: 06/17/2025
UPDATED: 07/29/2025
DUE: 02/17/2028
The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for exploratory and early-stage projects that focus on undruggable target classes within intractable human disease. ...
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
HHS-NIH11
POSTED: 06/17/2025
UPDATED: 06/17/2025
DUE: 05/07/2028
The purpose of the NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00) program is to develop and maintain a strong cohort of independently funded dentist scientists dedicated t...
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
$11,000,000
HHS-NIH11
POSTED: 06/16/2026
UPDATED: 06/16/2026
DUE: 02/20/2029
The purpose of this Notice of Funding Opportunity (NOFO) is to support the preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics for t...
NIDCR Prospective Observational or Biomarker Validation Study Cooperative Agreement (U01 Clinical Trial Not Allowed)
HHS-NIH11
POSTED: 06/16/2026
UPDATED: 06/16/2026
DUE: 07/05/2029
This Notice of Funding Opportunity (NOFO) will support, through the cooperative agreement mechanism, investigator-initiated observational studies or biomarker validation studies that require prospecti...
NIAID Clinical Trial Implementation Cooperative Agreement (U01 Clinical Trial Required)
HHS-NIH11
POSTED: 06/16/2026
UPDATED: 06/16/2026
DUE: 07/05/2029
This notice of funding opportunity (NOFO) encourages applications for implementation of investigator-initiated, milestone driven clinical trials that need enhanced oversight, and as applicable, includ...