Pilot Projects to Enhance the Human Virome Program (R03, Clinical Trials Not Allowed)

HHS-NIH11 RFA-RM-25-006
Posted: Sep 22, 2025 12:00:00 AM EDT
Closes: 11/24/2025

Funding Information

Award Ceiling
$100,000

Description

The Common FundHuman Virome Program(HVP) aims to extensively and comprehensively characterize the human virome and create tools, models, and methods that will enable an in-depth study of its variation and composition in relation to host factors and its influence on health and disease.
The purpose of this NOFO is to support small pilot projects that extend the goals of the HVP, including further validating, improving, and complementing existing and newly developed tools from the HVP program by leveraging human specimens collected from the cohorts under the program; samples from animals to promote the refinement, utilization, and translation of these tools to better serve the goals of the HVP program; expanding existing cohorts and/or biospecimen sampling sites for virome characterization; developing tools and methods to study the human virome; and defining interactions between the human virome and host. These pilot projects will encourage collaboration across the HVP and expand the consortium. Pilot projects should not overlap with existing HVP efforts. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources.

Synopsis

The Common FundHuman Virome Program(HVP) aims to extensively and comprehensively characterize the human virome and create tools, models, and methods that will enable an in-depth study of its variation and composition in relation to host factors and its influence on health and disease.
The purpose of this NOFO is to support small pilot projects that extend the goals of the HVP, including further validating, improving, and complementing existing and newly developed tools from the HVP program by leveraging human specimens collected from the cohorts under the program; samples from animals to promote the refinement, utilization, and translation of these tools to better serve the goals of the HVP program; expanding existing cohorts and/or biospecimen sampling sites for virome characterization; developing tools and methods to study the human virome; and defining interactions between the human virome and host. These pilot projects will encourage collaboration across the HVP and expand the consortium. Pilot projects should not overlap with existing HVP efforts. The R03 is intended to support small research projects that can be carried out in a short period of time with limited resources.

Eligibility

Eligible Applicants:
State governments City or township governments Native American tribal organizations (other than Federally recognized tribal governments) Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Special district governments Private institutions of higher education Native American tribal governments (Federally recognized) County governments Small businesses Independent school districts Public and State controlled institutions of higher education Public housing authorities/Indian housing authorities For profit organizations other than small businesses Others (see text field entitled "Additional Information on Eligibility" for clarification)
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U.S. Territory or Possession.

Funding Activity Categories

Health

CFDA Numbers

  • 93.310 - Trans-NIH Research Support

Contact Information

Agency: National Institutes of Health
Contact: National Institutes of Health
Phone: 301-402-2541
NIH Grants Information
grantsinfo@nih.gov

Additional Information

Document Type: synopsis
Opportunity Category: Discretionary
Version: 1
Last Updated: Sep 22, 2025 11:51:40 AM EDT

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